G-protein Activation (Q6773493): Difference between revisions

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Created claim: defining formula (P989): f_{11} = k_{11} \cdot x_R \cdot x_{\alpha\text{GDP}\beta\gamma}
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Latest revision as of 08:18, 11 July 2025

reaction describing the constitutive G-protein activation
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G-protein Activation
reaction describing the constitutive G-protein activation

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    The constitutive G-protein activation, where we simply use R2 without ligand. That is, we model the constitutive binding reaction as a net reaction consisting of first the switching of GTP and GDP, followed by the dissociation of the βγ-subunit from the GPCR complex.
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    f11=k11xRxαGDPβγ
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