WorldCOM Deliverable 1: Prevalence of ESBL subtypes in bacterial pathogens and a sequence database of selected alleles
DOI10.5281/zenodo.4019840Zenodo4019840MaRDI QIDQ6707816
Dataset published at Zenodo repository.
Owen Higgins, Arnoud H. M. van Vliet, Louise O'Connor, Terry J. Smith, Marwa M. Hassan, Dearbhaile Morris, Liam Burke, Roberto M. la Ragione
Publication date: 10 September 2020
Copyright license: Creative Commons Attribution 4.0 International
OHEJP Project: WorldCOM, Deliverable 1, Work Package 1. This dataset is connected to Work Package 1, Task1 of the WorldCOM consortium grant within the One Health EJP group. The aim was to analyse publicly available sequences for antimicrobial resistance genes associated with Salmonella, Campylobacter and E. coli. For the initial phase of this work package, we have focused on ESBL-related AMR genes. As these genes are absent from Campylobacter, we have not included this bacterium in these analyses, and have used the important pathogens Klebsiella and Acinetobacter. All types and subtypes of Extended Spectrum -Lactamases (ESBLs) and plasmid-mediated colistin resistance genes have been analysed for frequency among reported and extracted sequences. High frequency resistant genes subtypes have been highlighted for further sequence analysis to illustrate geographic distribution and geographic-specific single nucleotide polymorphisms (SNPs). The data shown are work in progress.
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