G-protein Activation

Available identifiers

MaRDI QIDQ6773493

reaction describing the constitutive G-protein activation

Description

The constitutive G-protein activation, where we simply use R2 without ligand. That is, we model the constitutive binding reaction as a net reaction consisting of first the switching of GTP and GDP, followed by the dissociation of the βγ-subunit from the GPCR complex.

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Defining Formula: $f_{11}=k_{11}\cdot x_R\cdot x_{\alpha \text{GDP}\beta \gamma }$

$k_{11}$ symbol represents Reaction Constant for G-protein Activation

$x_R$ symbol represents Number of Receptor Molecules

$x_{{\alpha }_{GDP}\beta \gamma }$ symbol represents Number of G-protein Molecules

$f_{11}$ symbol represents Propensity of G-protein Activation

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