iGEMME Missense Mutational Effect Predictions for Entire Human Proteome

DOI10.5281/zenodo.10671864Zenodo10671864MaRDI QIDQ6698402

Dataset published at Zenodo repository.

Author name not available (Why is that?)

Publication date: 16 February 2024

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Description

This dataset contains iGEMME single point mutation predictions of about ~19000 human proteins. In iGEMME predictions, only evolutionary data coming from multiple sequence alignment files is used. Description of the data and file structure This dataset contains iGEMME predictions for all human proteins. Data of each human protein is in a folder named after its uniprotID. Inside uniprotID folder, there is a subfolder called results that contain all input and output. An example results folder for uniprotID A0A0B4J245 will contain the following files: Raw igemme predictions (output file): A0A0B4J245_normPred_evolCombi_igemme.txt Ranksorted (between 0-1) igemme predictions in csv format (output file): A0A0B4J245_normPred_evolCombiTransposedRanksorted_igemme.csv Colabfold MSA file (input file): aliA0A0B4J245.fasta JET2 file containing JET scores for each amino acid (output file) : A0A0B4J245_jet_igemme.res Configuration file containing default parameters (output file): default.conf Log file (output file): igemme.log

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