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POSTm - MaRDI portal

POSTm (Q106295)

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Phylogeny-Guided OTU-Specific Association Test for Microbiome Data
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POSTm
Phylogeny-Guided OTU-Specific Association Test for Microbiome Data

    Statements

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    1.2
    6 June 2022
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    1.1
    30 April 2021
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    1.2
    7 June 2022
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    1.3
    13 December 2023
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    13 December 2023
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    Implements the Phylogeny-Guided Microbiome OTU-Specific Association Test method, which boosts the testing power by adaptively borrowing information from phylogenetically close OTUs (operational taxonomic units) of the target OTU. This method is built on a kernel machine regression framework and allows for flexible modeling of complex microbiome effects, adjustments for covariates, and can accommodate both continuous and binary outcomes.
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    Identifiers

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