A Lagrange-Gamma multihit dose-response model for risk assessment (Q1079913)
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scientific article; zbMATH DE number 3965298
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | A Lagrange-Gamma multihit dose-response model for risk assessment |
scientific article; zbMATH DE number 3965298 |
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A Lagrange-Gamma multihit dose-response model for risk assessment (English)
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1986
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This paper investigates the use of Lagrange-gamma multihit dose-response model to perform toxic chemical risk assessment. A biological interpolation of the model in terms of the occurrence of k ''hits'' to cause toxic response and a statistical interpretation in terms of a Lagrange-gamma tolerance density are given. The parameters of the model are obtained by the method of maximum likelihood and are used to estimate a virtual safe dose.
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Lagrange-gamma multihit dose-response model
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toxic chemical risk assessment
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Lagrange-gamma tolerance density
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maximum likelihood
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virtual safe dose
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