DRviaSPCN (Q113676)
From MaRDI portal
Drug Repurposing in Cancer via a Subpathway Crosstalk Network
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | DRviaSPCN |
Drug Repurposing in Cancer via a Subpathway Crosstalk Network |
Statements
13 January 2024
0 references
A systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.
0 references
expanded from: GPL (≥ 2) (English)
0 references
