On using index cases in the study of late-onset diseases (Q1304082)
From MaRDI portal
 | This is the item page for this Wikibase entity, intended for internal use and editing purposes. Please use this page instead for the normal view: On using index cases in the study of late-onset diseases |
scientific article; zbMATH DE number 1348350
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | On using index cases in the study of late-onset diseases |
scientific article; zbMATH DE number 1348350 |
Statements
On using index cases in the study of late-onset diseases (English)
0 references
5 October 1999
0 references
The method of index cases is used to construct a nonparametric estimator for the average cumulative risk of a late-onset disease in a population, under censoring, which is consistent even if the risk is suspected to vary with the individual in an unknown manner. In contrast, illustrations show the need for caution when index cases are used for testing whether a disease is familial.
0 references
Kaplan-meier estimator
0 references
familial disease
0 references
BRCA1
0 references
BRCA2
0 references
index cases
0 references
late-onset disease
0 references
0.7842642068862915
0 references
0.7808467745780945
0 references
0.7666882872581482
0 references
