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Estimating and interpreting effects from nonlinear exposure-response curves in occupational cohorts using truncated power basis expansions and penalized splines - MaRDI portal

Estimating and interpreting effects from nonlinear exposure-response curves in occupational cohorts using truncated power basis expansions and penalized splines (Q1664536)

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scientific article; zbMATH DE number 6925439
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English
Estimating and interpreting effects from nonlinear exposure-response curves in occupational cohorts using truncated power basis expansions and penalized splines
scientific article; zbMATH DE number 6925439

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    Estimating and interpreting effects from nonlinear exposure-response curves in occupational cohorts using truncated power basis expansions and penalized splines (English)
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    27 August 2018
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    Summary: Truncated power basis expansions and penalized spline methods are demonstrated for estimating nonlinear exposure-response relationships in the Cox proportional hazards model. R code is provided for fitting models to get point and interval estimates. The method is illustrated using a simulated data set under a known exposure-response relationship and in a data application examining risk of carpal tunnel syndrome in an occupational cohort.
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