Mathematical modelling of early diabetes mellitus (Q1820707)

A new stochastic model is presented for the study of chronic diseases in which individuals, who are identified as at high risk, are not necessarily expected to progress to develop the specific disease. The model considers the manifestation of the disease as a function of time as documented in prospective epidemiological studies of individual patients. An illustration is given with empirical data from the Boston Gestational Diabetes Study of 615 women who experienced glucose intolerance initialy confined to gestation (gestational diabetes) and were followed longitudinally for 16 years for incidence of diabetes mellitus.