Analysis of a tumor model as a multicomponent deformable porous medium (Q2141694)

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Analysis of a tumor model as a multicomponent deformable porous medium
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    Analysis of a tumor model as a multicomponent deformable porous medium (English)
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    25 May 2022
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    Summary: We propose a diffuse interface model to describe a tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a mechanical equilibrium equation with phase-dependent elasticity coefficients. The resulting PDE system couples two Cahn-Hilliard type equations for the tumor phase and the healthy phase with a PDE linking the evolution of the interstitial fluid to the pressure of the system, a reaction-diffusion type equation for the nutrient proportion, and a quasistatic momentum balance. We prove here that the corresponding initial-boundary value problem has a solution in appropriate function spaces.
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    tumor model
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    porous medium
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    diffuse interface model
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    Cahn-Hilliard equation
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    reaction-diffusion equation
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