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Computing optimal properties of drugs using mathematical models of single channel dynamics (Q2415216)

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Language	Label	Description	Also known as
English	Computing optimal properties of drugs using mathematical models of single channel dynamics	scientific article

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scholarly article

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Computing optimal properties of drugs using mathematical models of single channel dynamics (English)

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Mary M. Maleckar

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Glenn Terje Lines

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Computational and Mathematical Biophysics

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publication date

21 May 2019

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zbMATH Keywords

single channel dynamics

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drugs

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stochastic differential equations

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describes a project that uses

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MaRDI profile type

MaRDI publication profile

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full work available at URL

https://doi.org/10.1515/cmb-2018-0004

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MCMC for hidden Markov models incorporating aggregation of states and filtering

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Markov chain Monte Carlo fitting of single-channel data from inositol trisphosphate receptors

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Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states

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Computing characterizations of drugs for ion channels and receptors using Markov models

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A population density approach that facilitates large-scale modeling of neural networks: Analysis and an application in orientation tuning

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Computational cell biology

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The dynamics of luminal depletion and the stochastic gating of \(\operatorname{Ca}^{2 +} \)-activated \(\operatorname{Ca}^{2 +}\) channels and release sites

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Stochastic processes in cell biology

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HOW ANTIARRHYTHMIC DRUGS INCREASE THE RATE OF SUDDEN CARDIAC DEATH

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Defining candidate drug characteristics for Long-QT (LQT3) syndrome

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The effect of residual \(\operatorname{Ca}^{2 +}\) on the stochastic gating of \(\operatorname{Ca}^{2 +} \)-regulated \(\operatorname{Ca}^{2 +}\) channel models

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Mathematical physiology. I: Cellular physiology

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A note on a method for determining advantageous properties of an anti-arrhythmic drug based on a mathematical model of cardiac cells

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Finite Volume Methods for Hyperbolic Problems

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On the accuracy of operator splitting for the monodomain model of electrophysiology

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An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso

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Elements of Scientific Computing

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Identifiers

zbMATH Open document ID

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Mathematics Subject Classification ID

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zbMATH DE Number

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10.1515/CMB-2018-0004

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Sitelinks

Mathematics(1 entry)

mardi Publication:2415216

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