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Bayes estimation of toxicokinetic parameters in a four-stage hierarchical model (Q2753651)

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scientific article; zbMATH DE number 1670457
Language Label Description Also known as
English
Bayes estimation of toxicokinetic parameters in a four-stage hierarchical model
scientific article; zbMATH DE number 1670457

    Statements

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    11 November 2001
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    compartment models
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    linear hierarchical models
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    nonlinear hierarchical models
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    Hampel identifier
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    graphical analysis
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    maximum likelihood estimation
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    Bayes estimation of toxicokinetic parameters in a four-stage hierarchical model (English)
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    Contents (Chapter headings): 1. Introduction. 2. Ethylene and ethylene oxide. 2. Toxicokinetics and compartmental modelling. 4. Inhalation study with ethylene. 5. Population models. 6. Four-stage nonlinear hierarchical models: Combining EM algorithm and outlier identification. 7. Testing assumptions of overall first order kinetics. 8. Results. 9. Discussion.
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