Computer-aided design of arylphthalazines as potential smoothened receptor antagonists (Q2836555)
From MaRDI portal
 | This is the item page for this Wikibase entity, intended for internal use and editing purposes. Please use this page instead for the normal view: Computer-aided design of arylphthalazines as potential smoothened receptor antagonists |
scientific article; zbMATH DE number 6183432
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Computer-aided design of arylphthalazines as potential smoothened receptor antagonists |
scientific article; zbMATH DE number 6183432 |
Statements
Computer-aided design of arylphthalazines as potential smoothened receptor antagonists (English)
0 references
3 July 2013
0 references
smoothened receptor antagonists
0 references
activity-structure relations
0 references
molecular field topology analysis
0 references
comparative molecular similarity indices analysis
0 references
The goal is to propose a model of activity-structure relations for antagonists. A comparative analysis of activity charts for molecular field topology analysis and comparative molecular similarity indices analysis demonstrates a good coherence. A virtual screening method is used for the synthesis of the new antagonists.
0 references
