flexmsm (Q5984138)

A general estimation framework for multi-state Markov processes with flexible specification of the transition intensities. The log-transition intensities can be specified through Generalised Additive Models which allow for virtually any type of covariate effect. Elementary specifications such as time-homogeneous processes and simple parametric forms are also supported. There are no limitations on the type of process one can assume, with both forward and backward transitions allowed and virtually any number of states.