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Theoretical quantification of the polyvalent binding of nanoparticles coated with peptide-major histocompatibility complex to T cell receptor-nanoclusters - MaRDI portal

Theoretical quantification of the polyvalent binding of nanoparticles coated with peptide-major histocompatibility complex to T cell receptor-nanoclusters (Q6157790)

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scientific article; zbMATH DE number 7700137
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English
Theoretical quantification of the polyvalent binding of nanoparticles coated with peptide-major histocompatibility complex to T cell receptor-nanoclusters
scientific article; zbMATH DE number 7700137

    Statements

    Theoretical quantification of the polyvalent binding of nanoparticles coated with peptide-major histocompatibility complex to T cell receptor-nanoclusters (English)
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    22 June 2023
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    polyvalent biding
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    pMHC-coated nanoparticles
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    T cell receptors
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    multiscale model
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    dissociation constant
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    Gibbs free energy
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    insertion probability
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    TCR nanoclusters
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    density of bound and triggered TCRs
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    cooperativity
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