Stochastic behavior of within-host progression in primary dengue infection (Q6584724)
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scientific article; zbMATH DE number 7893827
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Stochastic behavior of within-host progression in primary dengue infection |
scientific article; zbMATH DE number 7893827 |
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Stochastic behavior of within-host progression in primary dengue infection (English)
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8 August 2024
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The paper studies stochastic behavior of within-host progression in primary dengue infection. It introduces a deterministic nonlinear ordinary differential equation model characterizing the in-host progression of primary dengue virus infection. The factors influencing viral persistence in the body for an extended period are explored. The paper conducts stochastic simulations of the model employing Gillespie's direct simulation algorithm and compares the results with those of the deterministic model. The stochastic model allows for incorporating uncertainties in the conditions that vary from person to person. Global stability of the equilibrium points, Deterministic results and sensitivity analysis are presented.
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primary dengue infection
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nonlinear dynamics of within-host progression
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immune response
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deterministic model
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stochastic simulations
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incubation period
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peak viremia time
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