Associated code and data for "A Practical Guideline for MicroRNA Sequencing Data Analysis in Chronic Lymphocytic Leukemia (doi: 10.1007/978-1-0716-4290-0_18)". (Q6700368)

This deposit contains the data, code, and analysis to recreate the results in the manuscript - Tuulikki Suomela, Liang Zhang, Julio Vera, Heiko Bruns, Xin Lai. A Practical Guideline for MicroRNA Sequencing Data Analysis in Chronic Lymphocytic Leukemia. Methods Mol. Biol., 2883, 403426. https://doi.org/10.1007/978-1-0716-4290-0_18. The pipeline allows users to perform end-to-end analysis of bulk miRNA sequencing data, including quality control of FastQ files, mapping of read counts to miRNA genes using miRBase or Reference genome, quantification of miRNA read counts, differential gene expression analysis using DEseq2, gene set enrichment analysis using curated cancer hallmark gene sets, and identification of miRNA targets. If you have used the code for your research, please cite the original publication. Thank you very much.