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Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system - MaRDI portal

Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system (Q911499)

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scientific article; zbMATH DE number 4141851
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English
Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system
scientific article; zbMATH DE number 4141851

    Statements

    Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system (English)
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    1989
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    parameter estimation
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    Concentration-time curves
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    anticancer drug
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    metabolites
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    enzymatic pathways
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    enzymatic nonlinear model
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    multivariate measurement error
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    multinormal distribution
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    variance model
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    maximum likelihood principle
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    pharmacokinetic model
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    residual analysis
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    intrakinetic and interkinetic variabilities
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