Plasma circulating microRNA-expression quantitative trait loci (eQTLs) data in the Rotterdam Study

DOI10.5281/zenodo.13869398Zenodo13869398MaRDI QIDQ6683820

Dataset published at Zenodo repository.

Author name not available (Why is that?)

Publication date: 1 October 2024

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Description

The dataset contains GWAS summary statistics for 2,083 plasma circulating microRNAs, obtained from nearly 2,178 participants of the Rotterdam Study.The dataset includes three files, as outlined below: File1: SNP_reference_file_maf0.01_Rsq0.7.txt A reference file for SNPs with good imputation quality (Rsq 0.7) and minor allele frequency 0.01 among participants included in our GWAS in the Rotterdam Study (N=2,178). The headers are: SNP: rsID chr: chromosome number according to GRCh37 bp: basepair position according to GRCh37 effect_allele: effect allele other_allele: other allele eaf: effect allele frequency File2: miReQTLs_1e-5_maf0.01_Rsq0.7.txt Summary statistics for all SNPs significantly associated with 2083 miRNAs (p-value 1e-5), filtered by minor allele frequency 0.01 and Rsq 0.7. The headers are: SNP: rsID beta: effect estimate se: standard error pval: p-value miRNA: miRNA ID File3: miReQTLs_nominal_sig.csv.gz Summary statistics for all SNPs nominally associated with 2083 miRNAs (p-value 0.05). The headers are: RSID: SNP ID p-value: p-value phenotype: miRNA SE: standard error BETA: effect estimate The SNP allelic information and frequency can be found in the reference file (File1). For more information, please contact: m.ghanbari@erasmusmc.nl

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