Sequential activation of metabolic pathways: a dynamic optimization approach

DOI10.1007/s11538-009-9427-5zbMath1179.92026OpenAlexW1970707057WikidataQ51834066 ScholiaQ51834066MaRDI QIDQ1048264

Brian P. Ingalls, Dimitrios Kalamatianos, Diego A. Oyarzún, Middleton, Richard H.

Publication date: 11 January 2010

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-009-9427-5

zbMATH Keywords

dynamic optimizationmetabolic regulationmetabolic dynamics

Mathematics Subject Classification ID

Dynamic programming in optimal control and differential games (49L20) Dynamic programming (90C39) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (10)

CMMSE-17: general analytical laws for metabolic pathways ⋮ Solving linear unbranched pathways with Michaelis-Menten kinetics using the Lambert \(W\)-function ⋮ Optimal performance of the tryptophan operon of \textit{E. coli}: a stochastic, dynamical, mathematical-modeling approach ⋮ Optimal control of a linear unbranched chemical process with \(n\) steps: the quasi-analytical solution ⋮ Exact probability distributions of selected species in stochastic chemical reaction networks ⋮ Cyclic coordinate descent in a class of bang-singular-bang problems ⋮ Influence of enzyme production dynamics on the optimal control of a linear unbranched chemical process ⋮ Dynamic optimization of metabolic networks coupled with gene expression ⋮ Dynamical Analysis and Optimization of a Generalized Resource Allocation Model of Microbial Growth ⋮ Sensitivity analysis of a linear and unbranched chemical process with \(n\) steps

Uses Software

• PROPT
• TOMSYM

Cites Work

• Is maximization of molar yield in metabolic networks favoured by evolution?
• Time ordering of gene coexpression
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