Towards an optimal drug-delivery regimen for methotrexate chemotherapy

DOI10.1016/0096-3003(83)90002-4zbMath0517.92005OpenAlexW1975676039MaRDI QIDQ1053635

J. Blot

Publication date: 1983

Published in: Applied Mathematics and Computation (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0096-3003(83)90002-4

zbMATH Keywords

compartment modelcancer chemotherapymaximum tumor-cell damagemethotrexate chemotherapyminimum normal-cell damageoptimal drug-delivery regimen

Mathematics Subject Classification ID

Linear systems in control theory (93C05) Medical applications (general) (92C50) Chemical kinetics in thermodynamics and heat transfer (80A30) Control/observation systems governed by ordinary differential equations (93C15) Physiological, cellular and medical topics (92Cxx)

Cites Work

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