Some mixed models of carcinogenesis

DOI10.1016/0895-7177(88)90089-1zbMath0668.92001OpenAlexW1967947450MaRDI QIDQ1118537

S. H. Smith

Publication date: 1988

Published in: Mathematical and Computer Modelling (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0895-7177(88)90089-1

zbMATH Keywords

two-stage modelsstochastic independencemutation ratestumor cellsage-dependentmixed model of carcinogenesisnormal stem cellsaccessory cancer genesanti oncogenesexpected incidence functionsintermediate cellsMoolgavkar-Venzon-Knudson Modelnon- homogeneous birth-death processnon-overlapping subpopulationsoncogenesone-stage modelsprobabilities of the number of tumorsprobability generating function techniqueretinoblastomaTumor cell growthWilm's tumor

Mathematics Subject Classification ID

Applications of branching processes (60J85) Medical applications (general) (92C50)

Cites Work

• Unnamed Item
• A mixed model of carcinogenesis with applications to retinoblastoma
• On the distribution of the number of mutants at the hypoxanthine-quanine phosphoribosal transferase locus in Chinese hamster ovary cells
• On the assessment of effects of environmental agents on cancer tumor development by a two-stage model of carcinogenesis
• Two-event models for carcinogenesis: Incidence curves for childhood and adult tumors
• A nonhomogeneous two-stage model of carcinogenesis
• On Distribution Theories for the Number of Mutants in Cell Populations

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