A new approach for calculating association constants from macromolecule- ligand bindling isotherms

DOI10.1016/0025-5564(82)90052-9zbMath0486.92030OpenAlexW1979869039MaRDI QIDQ1165206

William Squire

Publication date: 1982

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(82)90052-9

zbMATH Keywords

new approachcalculating association constantsextended Scatchard methodmacromolecule-ligand binding isothermsVandermonde systems of linear equations

Mathematics Subject Classification ID

Numerical computation using splines (65D07) Iterative numerical methods for linear systems (65F10) Numerical integration (65D30) Chemistry (92Exx)

Cites Work

• An algorithm for smoothing, differentiation and integration of experimental data using spline functions
• Solution of Vandermonde systems of equations

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