A nonlinear numerical model of percutaneous drug absorption

DOI10.1016/0025-5564(92)90054-ZzbMath0738.92007OpenAlexW2068375049WikidataQ52421738 ScholiaQ52421738MaRDI QIDQ1183727

S. Singh

Publication date: 28 June 1992

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(92)90054-z

zbMATH Keywords

permeability coefficientlag timeinitial/boundary-value problemsimple membrane modeldata analysis of in vitro experimentsdual-sorption modelnonlinear partial differential equation of parabolic typenumerical differentiation and integration procedurespercutaneous drug absorptionpharmacokinetic profiles

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Finite difference methods for boundary value problems involving PDEs (65N06)

Related Items (4)

A repeated-dose model of percutaneous drug absorption ⋮ Lag time in the dual sorption model for percutaneous absorption with finite skin-receptor boundary clearance ⋮ Higher-order parallel methods for a model of percutaneous drug absorption ⋮ A sequential algorithm for the nonlinear dual-sorption model of percutaneous drug absorption

Cites Work

• An Algorithm for Least-Squares Estimation of Nonlinear Parameters
• A method for the solution of certain non-linear problems in least squares
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