The study of combined action of agents using differential geometry of dose-effect surfaces

DOI10.1007/BF02459931zbMath0747.92018WikidataQ52414496 ScholiaQ52414496MaRDI QIDQ1194427

Gabriel K. Y. Lam

Publication date: 27 September 1992

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

zbMATH Keywords

differential geometryGaussian curvatureself-interactioncombined action of agentsdose- effect surfacesgraphic surfacesline curvature of a dose-effect curve

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Physiological, cellular and medical topics (92C99)

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The differential aspects of the linear isobole in the study of combined action of agents

Cites Work

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• General Models for the Joint Action of Mixtures of Drugs