A unified framework for variance component estimation with summary statistics in genome-wide association studies

DOI10.1214/17-AOAS1052zbMath1383.62305OpenAlexW2951217122WikidataQ52668235 ScholiaQ52668235MaRDI QIDQ127747

Xiang Zhou, Peng Zhang

Publication date: 1 December 2017

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://projecteuclid.org/euclid.aoas/1514430276

zbMATH Keywords

MINQUEsummary statisticsmethod of momentslinear mixed modelvariance componentgenome-wide association studies

Mathematics Subject Classification ID

Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Related Items (5)

REMI: REGRESSION WITH MARGINAL INFORMATION AND ITS APPLICATION IN GENOME-WIDE ASSOCIATION STUDIES ⋮ An algorithm for searching optimal variance component estimators in linear mixed models ⋮ rMVP ⋮ GEMMA ⋮ Variable prioritization in nonlinear black box methods: a genetic association case study

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