Accurate Monte Carlo estimation of very small \(p\)-values in Markov chains

zbMath0926.65005MaRDI QIDQ1297844

John W. Wilbur

Publication date: 14 September 1999

Published in: Computational Statistics (Search for Journal in Brave)

zbMATH Keywords

algorithmtail probabilityprobability densitydiscrete Markov chainprotein threading modelsmall probability

Mathematics Subject Classification ID

Markov processes: estimation; hidden Markov models (62M05) Monte Carlo methods (65C05) Markov chains (discrete-time Markov processes on discrete state spaces) (60J10) Biochemistry, molecular biology (92C40) Numerical analysis or methods applied to Markov chains (65C40)

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The combinatorics and extreme value statistics of protein threading

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