Design of cross-over trials for pharmacokinetic studies

DOI10.1016/S0378-3758(98)00221-3zbMath0933.62113OpenAlexW2078186230WikidataQ127323757 ScholiaQ127323757MaRDI QIDQ1300941

V. Pereyra

Publication date: 2 April 2000

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0378-3758(98)00221-3

zbMATH Keywords

D-optimalitypharmacokinetics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Related Items (4)

Evaluation of the Fisher information matrix in nonlinear mixed effect models using adaptive Gaussian quadrature ⋮ Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics ⋮ Optimal designs for nonlinear regression models with respect to non-informative priors ⋮ Optimal cross-over designs for nonlinear mixed models using a first-order expansion

Cites Work

• Information matrices for mixed effects models with applications to the optimality of repeated measurements designs
• Bayesian experimental design: A review
• The Equivalence of Two Extremum Problems
• Recent Developments in the Methods of Optimum and Related Experimental Designs
• Recent Advances in Nonlinear Experimental Design
• Optimum Experimental Designs for Properties of a Compartmental Model
• An extension of the General Equivalence Theorem to nonlinear models
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