Mutation load and mutation-selection-balance in quantitative genetic traits

DOI10.1007/BF00163878zbMath0823.92013OpenAlexW2066290609WikidataQ52384552 ScholiaQ52384552MaRDI QIDQ1320345

Josef Hofbauer, Reinhard Bürger

Publication date: 31 October 1995

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/bf00163878

zbMATH Keywords

boundsmutant distributionfirst-order approximationsglobal linkage equilibriumequilibrium variancehouse-of-cards approximationmultilocus casemutation loadmutation-stabilizing-selection balanceorder of the error termquantitative genetic traitsreduction of equilibrium mean fitness

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

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Cites Work

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• Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle
• The selection mutation equation
• Moments, cumulants, and polygenic dynamics
• Dynamics of polygenic characters under selection
• Perturbations of positive semigroups and applications to population genetics
• Equilibrium Distributions of Continuous Polygenic Traits
• Possibility of extensive neutral evolution under stabilizing selection with special reference to nonrandom usage of synonymous codons.
• A simple model for the balance between selection and mutation
• A stochastic model concerning the maintenance of genetic variability in quantitative characters.

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