Retention of antigen on follicular dendritic cells and B lymphocytes through complement-mediated multivalent ligand-receptor interactions: theory and application to HIV treatment

DOI10.1016/S0025-5564(02)00091-3zbMath1007.92017OpenAlexW2047093581WikidataQ52043833 ScholiaQ52043833MaRDI QIDQ1603292

Alan S. Perelson, Ora E. Percus, Carla Wofsy, William S. Hlavacek, Jerome K. Percus

Publication date: 11 July 2002

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0025-5564(02)00091-3

zbMATH Keywords

immune memorybirth-death Markov chainB lymphocytesfollicular dendritic cellshuman immunodeficiency virus type Imultivalent ligand-receptor binding

Mathematics Subject Classification ID

Medical applications (general) (92C50) Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20)

Cites Work

• Receptor clustering on a cell surface. III. Theory of receptor cross- linking by multivalent ligands: Description by ligand states
• Dissociation of HIV-1 from follicular dendritic cells during HAART: Mathematical analysis

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