Exploring the role of the immune response in preventing antibiotic resistance

DOI10.1016/J.JTBI.2008.10.025zbMath1400.92318OpenAlexW2065936095WikidataQ44028719 ScholiaQ44028719MaRDI QIDQ1617454

Andreas Handel, Elisa Margolis, Bruce R. Levin

Publication date: 8 November 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc5814249

zbMATH Keywords

immune responsedrug resistanceantibiotic treatmentbacterial infection dynamicsmutant selection window

Mathematics Subject Classification ID

Medical epidemiology (92C60)

Related Items (9)

Modeling inoculum dose dependent patterns of acute virus infections ⋮ An optimal control problem applied to plasmid-mediated antibiotic resistance ⋮ Within-host bacterial growth dynamics with both mutation and horizontal gene transfer ⋮ Optimal dosing strategy and sensitivity analysis of a within-host drug resistance model with continuous and impulsive drug treatment ⋮ THE MATHEMATICAL ANALYSIS OF THE MODEL OF ANTIBIOTIC-RESISTANT BACTERIA AND THE IMMUNE CELLS ⋮ Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment ⋮ Minimal models of growth and decline of microbial populations ⋮ Mathematical models for within-host competition of malaria parasites ⋮ A MODEL ON BACTERIAL RESISTANCE CONSIDERING A GENERALIZED LAW OF MASS ACTION FOR PLASMID REPLICATION

Cites Work

• Modeling immune responses with handling time
• Models of CD8+ responses: 1. what is the antigen-independent proliferation program
• The dynamics of bacterial infection, innate immune response, and antibiotic treatment

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