The role of extracellular potassium dynamics in the different stages of ictal bursting and spreading depression: A computational study

DOI10.1016/J.JTBI.2009.01.032zbMath1402.92084OpenAlexW2003102260WikidataQ45985607 ScholiaQ45985607MaRDI QIDQ1620798

Markus A. Dahlem, Gerson Florence, Antônio-Carlos G. Almeida, José W. M. Bassani, Juergen Kurths

Publication date: 14 November 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.01.032

zbMATH Keywords

bifurcationexcitabilityspreading depressionextracellular potassium concentrationictal bursting

Mathematics Subject Classification ID

Neural biology (92C20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Related Items (5)

A multidomain model for ionic electrodiffusion and osmosis with an application to cortical spreading depression ⋮ A unified physiological framework of transitions between seizures, sustained ictal activity and depolarization block at the single neuron level ⋮ Extracellular potassium dynamics in the hyperexcitable state of the neuronal ictal activity ⋮ Metabolism plays a central role in the cortical spreading depression: evidence from a mathematical model ⋮ Unnamed Item

Uses Software

• XPPAUT

Cites Work

• Identifying essential conditions for refractoriness of Leão's spreading depression -- computational modeling
• Topological and phenomenological classification of bursting oscillations
• Weakly connected neural networks
• Role of potassium lateral diffusion in non-synaptic epilepsy: a computational study
• Simulating, Analyzing, and Animating Dynamical Systems

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