Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway

DOI10.1016/J.JTBI.2009.03.009zbMath1402.92170OpenAlexW2059627090WikidataQ46082517 ScholiaQ46082517MaRDI QIDQ1624346

Frédéric Dayan, Elisabeth Pécou, Jacques Pouysségur, Marc Monticelli

Publication date: 16 November 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.03.009

zbMATH Keywords

mathematical modelgene expressionHIFoxygen sensorsswitch-like behavior

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Physiological flow (92C35)

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Modeling the dynamics of hypoxia inducible factor-\(1\alpha\) (HIF-\(1\alpha\)) within single cells and 3D cell culture systems

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