A trade-off between neutrality and adaptability limits the optimization of viral quasispecies

DOI10.1016/j.jtbi.2009.07.034zbMath1403.92163OpenAlexW2043393264WikidataQ43923149 ScholiaQ43923149MaRDI QIDQ1628840

Ester Lázaro, Jacobo Aguirre, Susanna C. Manrubia

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.07.034

zbMATH Keywords

growth ratebottleneckmutation-selection equilibriumfitnessrecovery timegenetic robustnessout-of-equilibrium competition

Mathematics Subject Classification ID

Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (2)

Virus replication as a phenotypic version of polynucleotide evolution ⋮ Redundancy-selection trade-off in phenotype-structured populations

Cites Work

• Adaptive evolution on neutral networks
• Stationary mutant distributions and evolutionary optimization

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