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Tuning cell differentiation patterns and single cell dynamics by regulating proteins' functionalities in a toggle switch

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Publication:1628913
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DOI10.1016/j.jtbi.2009.08.024zbMath1403.92023OpenAlexW2079592589WikidataQ37588128 ScholiaQ37588128MaRDI QIDQ1628913

Olli Yli-Harja, Andre S. Ribeiro, Shannon Healy, Xiaofeng Dai

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.08.024


zbMATH Keywords

cell differentiationtoggle switchfunctional proteinfunctionality regulationnon-functional protein


Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Developmental biology, pattern formation (92C15) Cell biology (92C37)



Uses Software

  • SGN Sim


Cites Work

  • Variability of the distribution of differentiation pathway choices regulated by a multipotent delayed stochastic switch
  • Studying genetic regulatory networks at the molecular level: delayed reaction stochastic models
  • Noisy attractors and ergodic sets in models of gene regulatory networks




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