Elucidation of T cell signalling models

DOI10.1016/j.jtbi.2009.10.017zbMath1403.92057OpenAlexW2084194698WikidataQ60473731 ScholiaQ60473731MaRDI QIDQ1629053

Jon Timmis, Andrew Greensted, Nick D. L. Owens, A. M. Tyrrell

Publication date: 11 December 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2009.10.017

zbMATH Keywords

stochastic modellingkinetic proofreadingnegative feedbackcontinuous time Markov chainCD8, SHP1, ERKT cell tunability

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (1)

The receptor density algorithm

Uses Software

• Expokit

Cites Work

• Stochastic effects and bistability in T cell receptor signaling
• Coreceptor CD8-driven modulation of T cell antigen receptor specificity
• Numerical Methods in Markov Chain Modeling
• Markov Chains
• Expokit
• Nineteen Dubious Ways to Compute the Exponential of a Matrix, Twenty-Five Years Later

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