Coated platelets introduce significant delay in onset of peak thrombin production: theoretical predictions

DOI10.1016/J.JTBI.2018.05.021zbMath1400.92149OpenAlexW2804408846WikidataQ88758122 ScholiaQ88758122MaRDI QIDQ1642665

Mikhail A. Panteleev, Modepalli Susree, Mohan Anand

Publication date: 15 June 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2018.05.021

zbMATH Keywords

coagulationmechanistic modelcoated plateletsdose-dependencethrombin

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Physiology (general) (92C30)

Cites Work

• A mathematical model for in vitro coagulation of blood: role of platelet count and inhibition
• A model for the formation, growth, and lysis of clots in quiescent plasma. A comparison between the effects of antithrombin III deficiency and protein C deficiency
• A mathematical model of lipid-mediated thrombin generation
• Reaction Mechanisms and Kinetic Constants used in Mechanistic Models of Coagulation and Fibrinolysis
• A Model Incorporating Some of the Mechanical and Biochemical Factors Underlying Clot Formation and Dissolution in Flowing Blood

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