Mathematical modeling of cellular cross-talk between endothelial and tumor cells highlights counterintuitive effects of VEGF-targeted therapies

DOI10.1007/s11538-017-0273-6zbMath1394.92059OpenAlexW2609463043WikidataQ47325265 ScholiaQ47325265MaRDI QIDQ1648957

Trachette L. Jackson, Harsh Vardhan Jain

Publication date: 5 July 2018

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-017-0273-6

zbMATH Keywords

mathematical modelanti-VEGF therapiescellular cross-talk

Mathematics Subject Classification ID

Medical applications (general) (92C50) Cell biology (92C37)

Related Items (3)

Mathematical oncology ⋮ A Delayed Dynamical Model Describing the Effect of Tumor-Induced Vascular Endothelial Growth Factor on Angiogenesis: Backward Bifurcations and Global Dynamics ⋮ Mathematics + Cancer: An Undergraduate "Bridge" Course in Applied Mathematics

Uses Software

• SAFE Toolbox

Cites Work

• Modeling the VEGF-Bcl-2-CXCL8 pathway in intratumoral agiogenesis

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