Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2

DOI10.1016/j.jtbi.2018.02.020zbMath1397.92201OpenAlexW2793708880WikidataQ52373541 ScholiaQ52373541MaRDI QIDQ1649390

Mohammad Farhan Khan, Tobias von der Haar, Sarah K. Spurgeon

Publication date: 6 July 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://kar.kent.ac.uk/66562/1/JTB-D-17-00662R1%20self%20archived%20version.pdf

zbMATH Keywords

robustnesstranslationcontrol engineeringprotein synthesiseIF2eIF2BGcn2translational control

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Uses Software

• Matlab
• ode23
• ode45
• Ode15s
• ode113
• ode23s
• MATLAB ODE suite

Cites Work

• A mechanistic model of nutritional control of protein synthesis in animal tissues
• A mathematical modelling framework for elucidating the role of feedback control in translation termination
• The MATLAB ODE Suite
• Robustness in the presence of mixed parametric uncertainty and unmodeled dynamics
• An Algorithm for Least-Squares Estimation of Nonlinear Parameters
• The Quasi-Steady-State Assumption: A Case Study in Perturbation
• Unnamed Item

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