A mathematical model of the mevalonate cholesterol biosynthesis pathway

DOI10.1016/j.jtbi.2017.12.023zbMath1397.92223OpenAlexW2793225078WikidataQ47558205 ScholiaQ47558205MaRDI QIDQ1649447

José Domingo Salazar, Peter K. Sweby, Richard Currie, Frances Pool, Marcus J. Tindall

Publication date: 6 July 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://centaur.reading.ac.uk/74972/1/mevalonate-ACCEPTED.pdf

zbMATH Keywords

feedbacknonlinear ordinary differential equationHMGCRsqualene synthase

Mathematics Subject Classification ID

Periodic solutions to ordinary differential equations (34C25) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Uses Software

• Matlab

Cites Work

• Mathematical biology. Vol. 1: An introduction.
• A dynamical model of lipoprotein metabolism
• A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway