Optimal control applied to a generalized Michaelis-Menten model of CML therapy

DOI10.3934/dcdsb.2018022zbMath1376.92024OpenAlexW2765551512MaRDI QIDQ1678312

Helen Moore, Urszula Łedzewicz-Kowalewska

Publication date: 14 November 2017

Published in: Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/dcdsb.2018022

zbMATH Keywords

optimal controlMichaelis-Menten modelCML therapy

Mathematics Subject Classification ID

Applications of optimal control and differential games (49N90) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15)

Related Items (3)

On the role of pharmacometrics in mathematical models for cancer treatments ⋮ Optimization of combination therapy for chronic myeloid leukemia with dosing constraints ⋮ Optimal control for a mathematical model for chemotherapy with pharmacometrics

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• Optimal control for mathematical models of cancer therapies. An application of geometric methods
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