Feedback loops interlocked at competitive binding sites amplify and facilitate genetic oscillations

DOI10.1016/J.JTBI.2017.06.005zbMath1382.92137OpenAlexW2626267434WikidataQ47797266 ScholiaQ47797266MaRDI QIDQ1704225

Koichiro Uriu, Hajime Tei

Publication date: 9 March 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2017.06.005

zbMATH Keywords

phase differencecircadian clock\textit{Bmal1}synthetic genetic oscillators

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Biological rhythms and synchronization (92B25)

Cites Work

• Dynamical mechanism of \(Bmal1/Rev\)-\(erb\alpha\) loop in circadian clock
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• A model of the cell-autonomous mammalian circadian clock

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