Computational modeling of synergistic interaction between \(\alpha\)V\(\beta\)3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides

DOI10.1016/j.jtbi.2018.06.029zbMath1406.92143OpenAlexW2883161420WikidataQ57467572 ScholiaQ57467572MaRDI QIDQ1714301

Hojjat Bazzazi, Aleksander S. Popel, Yu Zhang, Mohammad Jafarnejad

Publication date: 31 January 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc6156791

zbMATH Keywords

computational modelmathematical modelsystems biologyVEGFintegrin signaling

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37) Systems biology, networks (92C42)

Uses Software

• SUNDIALS
• BioNetGen
• ImageJ

Cites Work

• SUNDIALS
• Receptor cross-talk in angiogenesis: mapping environmental cues to cell phenotype using a stochastic, Boolean signaling network model
• A methodology for performing global uncertainty and sensitivity analysis in systems biology

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