The role of telomere shortening in carcinogenesis: a hybrid stochastic-deterministic approach

DOI10.1016/j.jtbi.2018.09.003zbMath1406.92208OpenAlexW2950930859WikidataQ57478645 ScholiaQ57478645MaRDI QIDQ1716813

Natalia L. Komarova, Ignacio A. Rodriguez-Brenes, Dominik Wodarz

Publication date: 5 February 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc6234035

zbMATH Keywords

cancertelomerescomputational evolutionhybrid stochastic-deterministic methods

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40) Developmental biology, pattern formation (92C15)

Cites Work

• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• Cellular replication limits in the Luria-Delbrück mutation model

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