Considerations for using integral feedback control to construct a perfectly adapting synthetic gene network

DOI10.1016/J.JTBI.2010.07.034zbMath1407.92052OpenAlexW1968414492WikidataQ54023929 ScholiaQ54023929MaRDI QIDQ1726151

Jordan Ang, Brian P. Ingalls, Sangram Bagh, David R. McMillen

Publication date: 19 February 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2010.07.034

zbMATH Keywords

control systemssynthetic biologygene regulationregulatory feedback

Mathematics Subject Classification ID

Feedback control (93B52) Biochemistry, molecular biology (92C40) Control/observation systems governed by ordinary differential equations (93C15) Systems biology, networks (92C42)

Related Items (4)

Perfect adaptation of general nonlinear systems ⋮ Continuous-switch piecewise quadratic models of biological networks: application to bacterial growth ⋮ Mathematical immunology: from phenomenological to multiphysics modelling ⋮ Design principles for the analysis and construction of robustly homeostatic biological networks

Cites Work

• The internal model principle of control theory
• Adaptation and regulation with signal detection implies internal model
• Designer gene networks: Towards fundamental cellular control
• Output regulation of nonlinear systems

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