Variance in estimated pairwise genetic distance under high versus low coverage sequencing: the contribution of linkage disequilibrium

DOI10.1016/j.tpb.2017.08.001zbMath1393.92038OpenAlexW2596782378MaRDI QIDQ1746104

Yang Ni, Max Shpak, Jie Lü, Peter Mueller

Publication date: 24 April 2018

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1101/108928

zbMATH Keywords

linkage disequilibriumcoveragenext-generation sequencingcancer genomicsgenetic distancepooled sampling

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15) Genetics and epigenetics (92D10) Analysis of variance and covariance (ANOVA) (62J10)

Uses Software

• GATK
• BWA

Cites Work

• On the number of segregating sites in genetical models without recombination
• Statistical properties of segregating sites

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