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A measure to quantify the degree of cooperativity in overall titration curves

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Publication:1747707
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DOI10.1016/j.jtbi.2017.08.010zbMath1393.92013OpenAlexW2745037367WikidataQ53556061 ScholiaQ53556061MaRDI QIDQ1747707

Johannes W. R. Martini

Publication date: 27 April 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2017.08.010


zbMATH Keywords

cooperativityligand bindingHill coefficient


Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)


Related Items (2)

Cooperativity, absolute interaction, and algebraic optimization ⋮ Decoupled molecules with binding polynomials of bidegree \((n,2)\)



Cites Work

  • Cooperative binding: a multiple personality
  • A model for carrier-mediated biological signal transduction based on equilibrium ligand binding theory
  • The effect of site-to-site variability in ultrasensitive dose responses
  • A mathematical view on the decoupled sites representation
  • Unnamed Item




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