Tissue transport affects how treatment scheduling increases the efficacy of chemotherapeutic drugs

DOI10.1016/j.jtbi.2017.10.022zbMath1394.92053OpenAlexW2766754906WikidataQ47414202 ScholiaQ47414202MaRDI QIDQ1752414

Dan E. Ganz, Neil S. Forbes, Emily L. Brackett, Briana Sexton-Stallone

Publication date: 24 May 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2017.10.022

zbMATH Keywords

diffusionpharmacokineticschemotherapyretentioncell bindingoptimal treatment scheduletissue transport model

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

Related Items (1)

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Cites Work

• Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies

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