Latently infected cell activation: a way to reduce the size of the HIV reservoir?

DOI10.1007/S11538-012-9729-XzbMath1251.92020OpenAlexW2084402697WikidataQ47311740 ScholiaQ47311740MaRDI QIDQ1758088

Stanca M. Ciupe, Joseph M. Volpe, Jonathan E. Forde

Publication date: 7 November 2012

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-012-9729-x

zbMATH Keywords

latent reservoirimmune activation therapy

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Medical applications (general) (92C50) Computational methods for problems pertaining to biology (92-08)

Related Items (6)

Periodic Solutions of an Infected-Age Structured HIV Model with the Latent Factor and Different Transmission Modes ⋮ Analysis of HIV models with two time delays ⋮ An HIV model with age-structured latently infected cells ⋮ Dynamics of a new HIV model with the activation status of infected cells ⋮ Stochastic population switch may explain the latent reservoir stability and intermittent viral blips in HIV patients on suppressive therapy ⋮ Virus Dynamics

Cites Work

• HIV-1 infection and low steady state viral loads
• Duration of an intermittent episode of viremia
• Can the viral reservoir of latently infected \(CD4^{+}\) T cells be eradicated with antiretroviral HIV drugs?
• Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips
• Modeling HIV persistence, the latent reservoir, and viral blips

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